Thomas Berger. Vice-Chair Clinical Dept. of Neurology, Head of Neuroimmunology and Multiple Sclerosis Clinic & Research Unit 
Medical University of Innsbruck. Website
Clinical Dept. of Neurology. Anichstraße 35 , 6020 Innsbruck
Reseach subject
Stroke research, multiple sclerosis (MS), neurocritical care, parkinson’s disease (PD), multiple system atrophy (MSA), REM sleep behavior disorder, RBD, RLS, computational neuroscience
Summary
Grounded in long-lasting and excellent research collaborations the main research topics are related to pathomechanisms, clinical and therapeutic aspects of autoimmune CNS and PNS disorders: multiple sclerosis (MS), antibody-associated neurological disease (neuromyelitis optica [NMO], acute disseminated
encephalomyelitis or NMDAR-encephalitis) and immune neuropathies. Thus, scientific foci are the role of human autoantibodies directed against different CNS tissue antigens (mainly MOG, AQP4 and NMDA-R) and neutralizing antibodies in the monitoring of various MS treatments. These research activities are complementary to and translatable to our neurological laboratory diagnostics. In addition, extensive databases for MS and NMO have been established, which are of paramount importance for past and current national and international research activities.
Publications
- Reindl M, Linington C, Brehm U, Egg R, Dilitz E, Deisenhammer F, Berger T (1999): Antibodies against the myelin oligodendrocyte glycoprotein and the myelin basic protein in multiple sclerosis and other neurological diseases: a comparative study. Brain 122:2047-2056.
- Berger T, Rubner P, Schautzer F, Egg R, Ulmer H, Mayringer I, Dilitz E, Deisenhammer F, Reindl M (2003): Antimyelin antibodies as a predictor of clinically definite multiple sclerosis after a first demyelinating event. New Engl J Med 349:139-145.
- Di Pauli F, Mader S, Rostasy K, Kornek B, Ehling R, Deisenhammer F, Reindl M, Berger T (2011): Temporal dynamics of anti-MOG antibodies in CNS demyelinating diseases. Clin Immunol 138:247-254.
- Reindl M, Di Pauli F, Rostasy K, Berger T (2013): The spectrum of anti-myelin oligodendrocyte glycoprotein antibody mediated aquired human demyelinating diseases. Nature Rev Neurol 9:455-61.
- Bsteh G, Ehling R, Lutterotti A, Hegen H, Di Pauli F, Auer M, Deisenhammer F, Reindl M, Berger T (2016): Long-term clinical prognostic factors in relapsing-onset multiple sclerosis: Insights from a 10-year observational study. PloS One 11:e0158978.