Medical University of Innsbruck. Website
University Hospital for Internal Medicine I. Anichstraße 35,6020 Innsbruck
Gastroenterology, hepatology, endocrinology, metabolism, inflammation, diabetes mellitus, microbiota, non-alcoholic fatty liver disease, nutrition, inflammatory bowel diseases
The research focus of our department is translational research in the fields of inflammation and metabolism and is represented by several research groups. The major objective of our research activities is to improve clinical management of patients with chronic inflammatory disorders, such as Crohn’s disease, ulcerative colitis, type 2 diabetes or obesity. The major research topics are:
• the cause and effects of intestinal inflammation particularly in connection with diseases like Crohn’s disease and ulcerative colitis
• studies of the composition of the human microbiota and its effects on human health and different diseases
• role and mechanisms of insulin resistance in type 2 diabetes and non-alcoholic fatty liver disease with a focus on various diets
• bariatric surgery and metabolic/immunological effects on the host
• lipoprotein metabolism and atherosclerosis
- Moschen, A. R., et al. Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations. Cell Host Microbe 2016;19:455-69.
- Zoller, H., Tilg, H. Nonalcoholic fatty liver disease and hepatocellular carcinoma. Metabolism 2016;65:1151-60.
- Yu, J., et al. Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer. Gut 2017;66:70-8.
- Feng, Q., et al. Gut microbiome development along the colorectal adenoma-carcinoma sequence. Nat Commun 2015;6:6528.
- Tilg, H., Moschen, A. R. Mechanisms behind the link between obesity and gastrointestinal cancers. Best Pract Res Clin Gastroenterol 2014;28:599-610.