Marten Hornsveld (Postdoc at Deptartment of Cell and Chemical Biology, LUMC) receives a grant for the Eurolife Scholarship Program for Early Career Researchers. The grant of 7.500 euro is funded by the Directorate of Research Policy, LUMC.
Marten will visit the Department of Oncology-Pathology at Karolinska Institutet in Stockholm. During the 4-months project, from September until December 2019, he will study signal transduction pathways in pancreatic cancer associated fibroblasts.
Both detection and treatment of pancreatic cancer are obstructed by cancer associated fibroblast (CAFs) in the tumor microenvironment. Marten aims to uncover how CAFs support tumor growth and how to target supportive CAFs for therapeutic benefit, using human pancreatic tumor organoid co-culture models in the lab of prof. Peter ten Dijke (dept. CCB, LUMC). The PDGFRβ and TGFβ molecular signal transduction pathways are heavily involved in CAF regulation within the tumor microenvironment. Marten will work with Prof. Arne Östman at the Karolinska Institutet to explore promising targeting strategies of PDGFRβ and TGFβ pathway interplay in pancreatic CAFs.
The Eurolife Scholarship Programme facilitates research stays in laboratories at the 8 other Eurolife partner institutions, for a period of three to six months. The call is open to Early Career Researchers, including PhD-students.
LUMC procedure for Eurolife Scholarships (link: https://www.albinusnet.nl/organisatie/directoraten/onderzoek/nieuwsoverzicht/2017/november/EurolifeScholarship-Programme-Early-Career-Researchers/)
Visit the Eurolife website to read about the 4 other LUMC researchers who have previously been granted this Eurolife Scholarship.